TICK-VIRUS-HOST INTERACTIONS/INTERFACE/DETERMINANTS DURING ARBOVIRAL TRANSMISSION
- Development of a Small Animal Model for Deer Tick Virus Pathogenesis Mimicking Human Clinical Outcome. PLoS Negl Trop Dis. 2020 Jun 15;14(6):e0008359. doi: 10.1371/journal.pntd.0008359.
- Utilization of RNA in situ Hybridization to Understand the Cellular Localization of Powassan Virus RNA at the Tick-Virus-Host Interface. Front Cell Infect Microbiol. 2020 Apr 28;10:172. doi: 10.3389/fcimb.2020.00172
- Tick-Borne Encephalitis Virus Infection Alters the Sialome of Ixodes ricinus Ticks During the Earliest Stages of Feeding. Front Cell Infect Microbiol. 2020 Feb 18;10:41. doi: 10.3389/fcimb.2020.00041.
- Ixodes scapularis salivary gland microRNAs are differentially expressed during Powassan virus transmission. Nature Sci Rep. Hermance et al., 2019.
- Tick-Virus-Host Interactions at the Cutaneous Interface: The Nidus of Flavivirus Transmission. Viruses. Hermance et al 2018.
- Generation of a Lineage II Powassan Virus (Deer Tick Virus) cDNA Clone: Assessment of Flaviviral Genetic Determinants of Tick and Mosquito Vector Competence. Vector Borne Zoonotic Dis. Kenney et al 2018.
- Powassan virus: An emerging arbovirus of public health concern in North America. Vector Borne Zoonotic Dis. Hermance and Thangamani 2017.
- Transcriptional Immunoprofiling at the Tick-Virus-Host Interface during Early Stages of Tick-Borne Encephalitis Virus Transmission. Front. Cell. Infect. Microbiol. Thangamani et al 2017.
- Tick-borne viruses and biological processes at the tick-host-virus interface. Frontiers in Microbiology. Front Cell Infect Microbiol. Kazimirova et al 2017.
- Concurrent micro-RNA mediated silencing of tick-borne flavivirus replication in tick vector and in the brain of vertebrate host. Sci Rep. Tsetsarkin et al 2016.
- Immune Cell Targets of Infection at the Tick-Skin Interface during Powassan Virus Transmission. PLoS One. Hermance et al 2016.
- Ixodes scapularis saliva enhances Powassan virus transmission to the host, influencing its dissemination and the course of disease. Journal of Virology. Hermance and Thangamani 2016.
- Proinflammatory cytokines and chemokines at the skin interface during Powassan virus transmission. J Invest Dermatol. Hermance and Thangamani 2017.
- Host immune response to Dermacentor andersonii feeding. Front Microbiol. Heinze et al 2014.
- Early immunologic events at the tick-host interface. PLoS One. Heinze et al 2012.
- Transcriptional profiling of the murine cutaneous response during initial and subsequent infestations with Ixodes scapularis nymphs. Heinze et al 2011.
- Blood feeding by the Rocky Mountain spotted fever vector, Dermacentor andersoni, induces interleukin-4 expression by cognate antigen responding CD4+T cells. Parasites & Vectors Thangamani & Boppan a et al 2009.
- Differential expression of the salivary transcriptome of Aedes aegypti upon blood feeding. Parasites & Vectors. Thangamani and Wikel, 2009.
- SAAG-4 is a Novel Mosquito Salivary Protein that Programs Host CD4+ T Cells to Express IL-4. Parasite Immunol. Thangamani & Boppana et al 2009.
MOSQUITO-VIRUS-HOST INTERACTIONS/INTERFACE/DETERMINANTS DURING ARBOVIRAL TRANSMISSION
- Measuring Alphavirus Fidelity Using Non-Infectious Virus Particles. Viruses. 2020 May 15;12(5):E546. doi: 10.3390/v12050546.
- Viral RNA-dependent RNA polymerase mutants display an altered mutation spectrum resulting in attenuation in both mosquito and vertebrate hosts. PLoS Pathog. Warmbrod et al 2019.
- Zika virus alters the microRNA expression profile and elicits an RNAi response in Aedes aegypti mosquitoes. PLoS Negl Trop Dis. Saldaña 2017
- Discovery of mosquito saliva microRNAs during CHIKV infection. Maharaj et al 2015.
- Host immune response to mosquito-transmitted chikungunya virus differs from that elicited by needle inoculated virus. PLoS ONE. Thangamani et al 2015.
BIOLOGY OF DISEASE TRANSMISSION
- Heartland virus infection in hamsters deficient in type I interferon signaling: protracted disease course ameliorated by favipiravir. Virology. Westover et al 2017.
- An Overview of Animal Models for Arthropod-Borne Viruses. Comp Med. Reynolds et al 2017.
- Spinal Cord Ventral Horns and Lymphoid Organ Involvement in Powassan Virus Infection in a Mouse Model. Viruses. Santis et ak, 2016.
VECTOR COMPETENCY / CAPACITY TO TRANSMIT ARBOVIRUSES
- Insect-specific viruses detected in laboratory mosquito colonies: Implications for evaluating vector competence experiments. Am J Trop Med Hyg. Bolling et al 2015.
- Establishing Protocols for tick containment at Biosafety level 4. Pathog Dis. Thangamani and Bente, 2014.
- Experimental transmission of Mayaro virus by Aedes aegypti. Am J Trop Med Hyg. Long et al 2011.
- Influence of laboratory animal hosts on the life cycle of Hyalomma marginatum and implications for an in vivo transmission model for Crimean-Congo hemorrhagic fever virus. Front Cell Infect Microbiol. Gargili et al.
- Vertical transmission of Zika virus in Aedes aegypti mosquitoes. Am J Trop Med Hyg. Thangamani et al 2016.
- Experimental infection with and maintenance of cell fusing agent virus in Aedes aegypti. AJTMH. Contreras et al 2017.
- Culex quinquefasciatus and Aedes taeniorhynchus from the Gulf Coast are Refractory to Zika Virus Infection. Emerg Infect Dis. Hart et al, 2017.
TICK/INVERTEBRATE IMMUNITY
- Molecular cloning, structure and bait region splice variants of alpha-2-macroglobulin from the soft tick Ornithodoros moubata. Insect Biochem Mol Biol. Saravanan (Thangamani) et al 2003
- Characterization of an alphamacroglobulin-like glycoprotein isolated from the plasma of the soft tick Ornithodoros moubata. Eur J Biochem. Kopacek et al 2000.
- Structural Basis for a dual inhibition mechanism of a non classical kazal type inhibitor to regulate host and pathogen protease interactions. PLoS ONE Tulsidas et al, 2011.
- Modifying the substrate specificity of Carcinocscorpious rotundicauda serine protease inhibitor domain1 to target Thrombin. PLoS ONE. Tulsidas et al, 2010.
- A novel serine protease inhibitor acts as an immunomodulatory switch while maintaining homeostasis. J Innate Immun. Thangamani & Jiang et al 2009.
- Crystallization of a non-classical Kazal-type Carcinoscorpius rotundicauda serine protease inhibitor, CrSPI-1, complexed with subtilisin. Acta Cryst. Tulsidas et al, 2009.
- Spatial and temporal coordination of expression of immune response genes during Pseudomonas infection of horseshoe crab, Carcinoscorpius rotundicauda. Genes Immun Ding et al, 2005.
- The ancient origin of the complement system. EMBO J. Zhu et al , 2005.
ECOLOGY OF TICK AND TICK-BORNE DISEASES
- Detection of Rickettsiae, Borreliae, and Ehrlichiae in Ticks Collected from Walker County, Texas, 2017-2018. Insects. Mendell et al, 2019.
- Meeting the challenge of tick-borne disease control: A proposal for 1000 Ixodes genomes. Ticks Tick Borne Dis. Murgia et al 2019.
VECTOR CONTROL
- Expression of a Synthetic Gene for the Major Cytotoxin (Cyt1Aa) of Bacillus thuringiensis subsp. israelensis in the Chloroplast of Wild-Type Chlamydomonas. Biology (Basel). Kang et al 2018.
- Toward mosquito control with a green alga: Expression of Cry toxins of Bacillus thuringiensis subsp. israelensis (Bti) in the chloroplast of Chlamydomonas. Journal of applied Phycology. Kang et al 2017.